MOTS-c: Structure & Analytical Reference
MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene. The page summarizes its identity, research context, and documentation.
Reference identity
| Class | Mitochondrial Peptide |
| Origin | Short open reading frame within the mitochondrial 12S rRNA gene |
| Documentation | certificate on release |
About the molecule
MOTS-c is a mitochondrial-derived peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene.
Research context
MOTS-c has been studied as a regulator of metabolic homeostasis acting largely through the folate–AICAR–AMPK pathway, with reported roles in stress response and aging in research models. This is neutral reference information, not a statement of effect in humans.
References
According to PubMed: Wan W et al. (2023), doi:10.1186/s12967-023-03885-2.
How it is documented
Where analysis is published for a released batch, its certificate records the available identity and purity results. Look up the lot number on the vial to retrieve any published record.